Morphological changes accompanying compensatory lung growth after pneumonectomy in rats.
نویسندگان
چکیده
منابع مشابه
Compensatory Lung Growth After Pneumonectomy
Pneumonectomy, the surgical removal of a lung, elicits a number of anatomical changes within the thoracic cavity that augments the diffusion capacity of the remaining lung. Pneumonectomy directs the entire cardiac output into the remaining lung and creates an empty hemithorax that results in a shift of the mediastinum toward the vacated thoracic compartment. In a number of experimental animal m...
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BACKGROUND Several renal disorders affect the glomerular podocytes. Compensatory structural and functional changes have been observed in animals that have undergone unilateral renal ablation. These changes occur as a pliant response to quench the increased functional demand to maintain homeostasis of fluid and solutes. Nestin is an intermediate filament protein present in the glomerular podocyt...
متن کاملNeoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice.
Regeneration of the gas exchange area by induction of neoalveolarisation would greatly improve therapeutic options in destructive pulmonary diseases. Unilateral pneumonectomy is an established model to remove defined portions of gas exchange area and study mechanisms of compensatory lung growth. The question of whether new alveoli are added to the residual lung after pneumonectomy in mice was a...
متن کاملNeoalveolarization contributes to compensatory lung growth following pneumonectomy in mice
Regeneration of gas exchange area by induction of neoalveolarization would greatly improve therapeutic options in destructive pulmonary diseases. Unilateral pneumonectomy is an established model to remove defined portions of gas exchange area and study mechanisms of compensatory lung growth. We addressed the question whether new alveoli are added to the residual lung after pneumonectomy in mice...
متن کاملCompensatory lung growth after partial pneumonectomy enhances lung tumorigenesis induced by 3-methylcholanthrene.
In small mammals, partial pneumonectomy (PNX) elicits rapid hyperplastic compensatory growth of the remaining lung parenchyma to restore normal lung mass, structure, and function. In BALB mice subjected to PNX, compensatory lung growth is complete within 10 days. Because cellular hyperplasia contributes to the mechanism of tumor promotion by butylated hydroxytoluene (BHT), we hypothesized that ...
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ژورنال
عنوان ژورنال: Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
سال: 1991
ISSN: 0300-9173
DOI: 10.3143/geriatrics.28.210